The Department of Biochemistry &

Publications by previous and current graduate students

Hassan, Ali-Ali, (current student, 2006)

Al-Ali, H., Ragan, T. J., and *Harris, T. K. (2006) Reconstitution of modular PDK1 functions on trans-splicing of the regulatory PH and catalytic kinase domains. Bioconjugate Chem. (submitted).

Curtis Anderson, 2005

Anderson, C.L., Zundel, M.A., and Werner, R. 2005. Variable promoter usage and laternative splicing in five mouse connexin genes. Genomics 85, 238-244.

Anderson, C.L., Catoe, H. and Werner, R. 2006. MiR-206 regulates connexin43 expression during skeletal muscle development. Nucleic Acid Res. 34, 5863-5871.

Pfeifer, I., Anderson, C., Werner, R., and Oltra, E. 2004 Redefining the structure of the connexin43 gene: selective promoter usage and alternative splicing mechanisms yield transcripts with different translational efficiencies. Nucleic Acid Res. 32, 4550-4562.

Mercedes Arana, 2004

Arana ME, Song L, Tanguy Le Gac N, Parris DS, Villani G, Boehmer PE., On the role of proofreading exonuclease in bypass of a 1,2 d(GpG) cisplatin adduct by the herpes simplex virus-1 DNA polymerase. DNA Repair (Amst). 2004 Jun 3;3(6):659-69.

Arana ME, Haq B, Tanguy Le Gac N, Boehmer PE., Modulation of the herpes simplex virus type-1 UL9 DNA helicase by its cognate single-strand DNA-binding protein, ICP8. J Biol Chem. 2001 Mar 2;276(9):6840-5. Epub 2000 Dec 8.

Sampson DA, Arana ME, Boehmer PE., Cysteine 111 affects coupling of single-stranded DNA binding to ATP hydrolysis in the herpes simplex virus type-1 origin-binding protein. J Biol Chem. 2000 Jan 28;275(4):2931-7.

Asmaa Baker (current, 2002)

Briegel KJ, Baker A, Jain C., Genetics. 2006 Jan;172(1):7-15. Epub 2005 Oct 3. Identification and analysis of Escherichia coli ribonuclease E dominant-negative mutants.

Geortgeta Basturea, 2007

G.N. Basturea, K.E. Rudd and M.P. Deutscher. 2006. “Identification and Characterization of RsmE, the Founding Member of a New RNA Base Methyltransferase Family”. RNA, 12, 426-434.

Basturea GN, Deutscher MP., Substrate specificity and properties of the Escherichia coli 16S rRNA methyltransferase, RsmE. RNA. 2007 Nov;13(11):1969-76. Epub 2007 Sep 13.

Frank Boellmann, 2003

Voellmy R, Boellmann F., Chaperone regulation of the heat shock protein response. Adv Exp Med Biol. 2007;594:89-99. Review.

Guettouche T, Boellmann F, Lane WS, Voellmy R., Analysis of phosphorylation of human heat shock factor 1 in cells experiencing a stress. BMC Biochem. 2005 Mar 11;6:4.

Boellmann F, Guettouche T, Guo Y, Fenna M, Mnayer L, Voellmy R., DAXX interacts with heat shock factor 1 during stress activation and enhances its transcriptional activity. Proc Natl Acad Sci U S A. 2004 Mar 23;101(12):4100-5. Epub 2004 Mar 11.

Guo Y, Guettouche T, Fenna M, Boellmann F, Pratt WB, Toft DO, Smith DF, Voellmy R., Evidence for a mechanism of repression of heat shock factor 1 transcriptional activity by a multichaperone complex. J Biol Chem. 2001 Dec 7;276(49):45791-9. Epub 2001 Oct 2.

Chenglu Chen, 2008

C. Chen and M.P. Deutscher. 2005. “Elevation of RNase R in Response to Multiple Stress Conditions”. J. Biol. Chem., 280, 34393-34396.

Zhuanfen Chen, 2002

Cheng ZF, Deutscher MP. (Apr 10, 2003) Purification and characterization of the Escherichia coli exoribonuclease RNase R. Comparison with RNase II. J Biol Chem. 277(24):21624-9

Cheng ZF, Deutscher MP. (May 27, 2003) Quality control of ribosomal RNA mediated by polynucleotide phosphorylase and RNase R. Proc Natl Acad Sci U S A. 100(11):6388-93

Kaya Y, Ofengand J. (June 2003) A novel unanticipated type of pseudouridine synthase with homologs in bacteria, archaea, and eukarya. RNA. 9(6):711-721

Mark Del Campo, 2004

Del Campo M, Recinos C, Yanez G, Pomerantz SC, Guymon R, Crain PF, McCloskey JA, Ofengand J., Number, position, and significance of the pseudouridines in the large subunit ribosomal RNA of Haloarcula marismortui and Deinococcus radiodurans. RNA. 2005 Feb;11(2):210-9.

Kaya Y, Del Campo M, Ofengand J, Malhotra A., Crystal structure of TruD, a novel pseudouridine synthase with a new protein fold. J Biol Chem. 2004 Apr 30;279(18):18107-10. Epub 2004 Mar 3.

Del Campo M, Ofengand J, Malhotra A., Crystal structure of the catalytic domain of RluD, the only rRNA pseudouridine synthase required for normal growth of Escherichia coli. RNA. 2004 Feb;10(2):231-9.

Del Campo M, Ofengand J, Malhotra A., Purification and crystallization of Escherichia coli pseudouridine synthase RluD. Acta Crystallogr D Biol Crystallogr. 2003 Oct;59(Pt 10):1871-3. Epub 2003 Sep 19.

Ofengand J, Malhotra A, Remme J, Gutgsell NS, Del Campo M, Jean-Charles S, Peil L, Kaya Y., Pseudouridines and pseudouridine synthases of the ribosome. Cold Spring Harb Symp Quant Biol. 2001;66:147-59. Review.

Ofengand J, Del Campo M, Kaya Y., Mapping pseudouridines in RNA molecules. Methods. 2001 Nov;25(3):365-73.

Del Campo M, Kaya Y, Ofengand J. ,Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli. RNA. 2001 Nov;7(11):1603-15.

Gutgsell NS, Del Campo M, Raychaudhuri S, Ofengand J., A second function for pseudouridine synthases: A point mutant of RluD unable to form pseudouridines 1911, 1915, and 1917 in Escherichia coli 23S ribosomal RNA restores normal growth to an RluD-minus strain. RNA. 2001 Jul;7(7):990-8.

Sarath, Dhananjayan, 2008

S. Dhananjayan and Z. Nawaz. Ubiquitin and the control of transcription. 2005. Assays in Biochem., 41, 69-80.

S. C. Dhananjayan, S. Ramamoorthy, O. Y. Khan, A. Ismail, J. Sun, J. Slingerland, B. W. O'Malley, and Z. Nawaz. 2006. WW-domain binding protein-2 (WBP-2), an E6-AP interacting protein acts as a coactivator of estrogen and progesterone receptors. Mol Endocrinol., 20 (10): 2343-2354.

Darryl Horn (current 2005)

Fontanesi F, Soto IC, Horn D, Barrientos A., Am J Physiol Cell Physiol. 2006 Jun 7; [Epub ahead of print] Assembly of Mitochondrial Cytochrome c Oxidase, a Complicated and Highly Regulated Cellular Process.

Horn D., Fontanesi F., and Barrientos A. Exploring protein-protein interactions involving newly synthesized mitochondrial DNA encoded proteins. Methods in Molecular Biology: Membrane Traffic. Ales Vancura, ed. Humana Press, in press (2008)

Horn D. and Barrientos A. Mitochondrial Copper Metabolism and Delivery to Cytochrome c Oxidase. IUBMB Life. in press (August 2008)

Horn D., Al-ali H., and Barrientos A. Cmc1p is a Conserved Mitochondrial Twin Cx9C Protein Involved in Cytochrome c Oxidase Biogenesis. Mol and Cell Biol. in press (2008)

Antoni Barrientos, Karine Gouget, Darryl Horn, Ileana C Soto, and Flavia Fontanesi, Suppression mechanisms of COX assembly defects in yeast and human: Insights into the COX assembly process., BBA - Molecular Cell Research, in press (2008)

Alice Hudder, 2000

Werner, R. Editor of Gap Junctions, Proceedings of International Gap Junction conference, IOS Press, Amsterdam, 1998.

Schiavi, A., Hudder, A., and Werner, R. 1999. Connexin43 mRNA contains a functional internal ribosome entry site. FEBS Let. 464, 118-122.

Werner, R., and Hudder, A. 2000. Editors, Gap Junctions, Methods (Academic Press) volume 20, number 2.

Hudder, A., and Werner, R. 2000. Analysis of a CMTX mutation reveals an essential IRES element in the connexin32 gene. J. Biol. Chem. 275, 34586-34591.

Yusuf Kaya, 2006

Kaya, Y., Del Campo, M., Ofengand, J. & Malhotra, A. Crystal structure of TruD, a novel pseudouridine synthase with a new protein fold. J. Biol. Chem., 279:18107-18110, 2004.

Kaya, Y. Recinos, C. & Malhotra, A. Phylogenetic, biochemical and functional characterization of pseudouridine synthase TruD. In preparation.

Kaya Y, Ofengand J. ,A novel unanticipated type of pseudouridine synthase with homologs in bacteria, archaea, and eukarya. RNA. 2003 Jun;9(6):711-21.

Ofengand J, Del Campo M, Kaya Y., Mapping pseudouridines in RNA molecules. Methods. 2001 Nov;25(3):365-73.

Del Campo M, Kaya Y, Ofengand J., Identification and site of action of the remaining four putative pseudouridine synthases in Escherichia coli. RNA. 2001 Nov;7(11):1603-15.

Gutgsell N, Englund N, Niu L, Kaya Y, Lane BG, Ofengand J., Deletion of the Escherichia coli pseudouridine synthase gene truB blocks formation of pseudouridine 55 in tRNA in vivo, does not affect exponential growth, but confers a strong selective disadvantage in competition with wild-type cells. RNA. 2000 Dec;6(12):1870-81.

Claudiu Nelersa (current 2000)

Blits-Huizinga, C. T., Nelersa, C. M., Malhotra, A., & Liebl, D. J. Ephrins and their receptors: Binding versus Biology. IUBMB Life, 56:257-265, 2004.

Amitabh Nimoncar, 2003

Nimonkar AV, Le Gac NT, Villani G, Boehmer PE., Escherichia coli RecA promotes strand invasion with cisplatin-damaged DNA. Biochimie. 2006 May;88(5):535-42. Epub 2005 Dec 5.

Nimonkar AV, Boehmer PE., Role of protein-protein interactions during herpes simplex virus type 1 recombination-dependent replication. J Biol Chem. 2004 May 21;279(21):21957-65. Epub 2004 Mar 16.

Nimonkar AV, Boehmer PE., On the mechanism of strand assimilation by the herpes simplex virus type-1 single-strand DNA-binding protein (ICP8). Nucleic Acids Res. 2003 Sep 15;31(18):5275-81.

Nimonkar AV, Boehmer PE., Reconstitution of recombination-dependent DNA synthesis in herpes simplex virus 1. Proc Natl Acad Sci U S A. 2003 Sep 2;100(18):10201-6. Epub 2003 Aug 19.

Boehmer PE, Nimonkar AV., Herpes virus replication. IUBMB Life. 2003 Jan;55(1):13-22. Review.

Nimonkar AV, Boehmer PE., The herpes simplex virus type-1 single-strand DNA-binding protein (ICP8) promotes strand invasion. J Biol Chem. 2003 Mar 14;278(11):9678-82.

Nimonkar AV, Boehmer PE., In vitro strand exchange promoted by the herpes simplex virus type-1 single strand DNA-binding protein (ICP8) and DNA helicase-primase. J Biol Chem. 2002 Apr 26;277(17):15182-9. Epub 2002 Feb 6.

Elisa Oltra, 1999

Oltra, E. J., and Werner, R. 1998. Cloning of a potential regulatory protein involved in connexin43 gene expression. Gap Junctions, IOS Press, Amsterdam. Editor: R. Werner, pp. 321-325.

Oltra, E., Pfeifer, I., and Werner R. 2003. Ini, a small nuclear protein that enhances the response of the connexin43 gene to estrogen. Endocrinology 144, 3148-3158.

Oltra, E., Verde, F., Werner, R., and D'Urso, G. 2004. A novel RING-finger-like protein Ini1 is essential for cell cycle progression in fission yeast. J. Cell Sci. 117,967-74

Oltra, E., Pfeifer, I., and Werner R. 2003. Ini, a small nuclear protein that enhances the response of the connexin43 gene to estrogen. Endocrinology 144, 3148-3158.

Oltra, E., Verde, F., Werner, R., and D'Urso, G. 2004. A novel RING-finger-like protein Ini1 is essential for cell cycle progression in fission yeast. J. Cell Sci. 117,967-74

Ilene Pedroso (current, 2001)

Yanez GH, Khan SJ, Locovei AM, Pedroso IM, Fletcher TM., Biochem Biophys Res Commun. 2005 Mar 4;328(1):49-56. DNA structure-dependent recruitment of telomeric proteins to single-stranded/double-stranded DNA junctions.

Ingrid Pfeifer, 2004

Schiavi, A., Pfeifer, I. and Werner, R. 2004. The connexin43 gene is controlled by two separate estrogen responsive elements. Endocrinology 144, 3148-3158.

Meyer PR, Matsuura SE, Tolun AA, Pfeifer I, So AG, Mellors JW, Scott WA. (May 2002) Effects of specific zidovudine resistance mutations and substrate structure on nucleotide-dependant primer unblocking by human immunodeficiency virus type1 reverse transcriptase. Antimicrob Agents Chemother. 46(5):1540-5

Vanessa Pino, 2006

Pino V, Ramsauer VP, Salas P, Carothers Carraway CA, Carraway KL., Membrane mucin Muc4 induces density-dependent changes in ERK activation in mammary epithelial and tumor cells: role in reversal of contact inhibition. J Biol Chem. 2006 Sep 29;281(39):29411-20. Epub 2006 Aug 4.

Ramsauer VP, Pino V, Farooq A, Carothers Carraway CA, Salas PJ, Carraway KL., Muc4-ErbB2 complex formation and signaling in polarized CACO-2 epithelial cells indicate that Muc4 acts as an unorthodox ligand for ErbB2. Mol Biol Cell. 2006 Jul;17(7):2931-41. Epub 2006 Apr 19.

TJ. Ragan, (current student, 2001)

Gao, X., Yo, P., Keith, A., Ragan, T. J., and *Harris, T. K. (2003) Thermodynamically balanced inside-out (TBIO) PCR-based gene synthesis: a novel method of primer design for high-fidelity assembly of longer gene sequences. Nuc. Acids Res. 31(22), e143.

Sivapriya Ramamoorthy (current student, 2004)

Claudia Recinos (current 2004)

Kaya, Y. Recinos, C. & Malhotra, A. Phylogenetic, biochemical and functional characterization of pseudouridine synthase TruD. In preparation.

Sudol M, Recinos CC, Abraczinskas J, Humbert J, Farooq A., IUBMB Life. 2005 Dec;57(12):773-8. WW or WoW: the WW domains in a union of bliss.

Carmen Rios (current 2004)

Wiley DJ, Catanuto P, Fontanesi F, Rios C, Sanchez N, Barrientos A, Verde F. Bot1p is required for mitochondrial translation, respiratory function, and normal cell morphology in the fission yeast Schizosaccharomyces pombe. Eukaryot Cell. 2008, 619-629.

C.Rios, K.Chen, J.El Hokayem, M.Rieger, G. D'Ippolito, P.C. Schiller, 2008. Abstract. Self-Renewal Mechanisms of Human Stromal MIAMI cells. Cytotherapy, May 2008 Volume 10, Supplement 1

Wiriya Rutvisuttinunt, 2006

Meyer, P.R., Rutvisuttinunt, W., Matsuura, S.E., and Scott, W.A. Effect of nucleotide binding on the positioning of HIV-1 RT on a primer-template. 2002 Cold Spring Harbor Meeting on Retroviruses, May 21-26, Cold Spring Harbor, NY, Abs. 205 (2002).

Rutvisuttinunt, W., Meyer, P.R., and Scott, W.A. Exonuclease mapping of stable complexes of HIV-1 reverse transcriptase on a chain-terminated DNA primer-template. 3^rd HIV DRP Symposium on Antiviral Drug Resistance, Dec. 8-11, Chantilly, VA (2002).

Rutvisuttinunt, W., Meyer, P., Matsuura, S., Rangarajan, P., Zonarich, D., Mellors, J., So, A., and Scott, W. Stable complex formation between HIV-1 RT and primer-template in the presence of foscarnet. 2003 Cold Spring Harbor Meeting on Retroviruses, May 20-25, Cold Spring Harbor, NY (2003).

Rutvisuttinunt, W., Meyer, P., and Scott, W. Exonuclease mapping of HIV-1 RT in complexes with primer-template. 2003 Cold Spring Harbor Meeting on Retroviruses, May 20-25, Cold Spring Harbor, NY (2003).

Rutvisuttinunt, W., Meyer, P.R., Matsuura, S.E., Rangarajan, P., So, A.G., and Scott, W.A. (2004) Trapping HIV-1 reverse transcriptase in the pretranslocation position by foscarnet (phosphonoformic acid, PFA). AIDS 2004. XV International AIDS Conference, Bangkok, Thailand, July 11-16, 2004.

Subramanian K., Rutvisuttinunt W., Scott W., Myers R.S., The enzymatic basis of processivity in lambda exonuclease. Nucleic Acids Res. 31:1585-1596, 2003.

Adam Schiavi, 2000

Schiavi, A., Hudder, A., and Werner, R. 1999. Connexin43 mRNA contains a functional internal ribosome entry site. FEBS Let. 464, 118-122.

Schiavi, A., Pfeifer, I. and Werner, R. 2004. The connexin43 gene is controlled by two separate estrogen responsive elements. Endocrinology 144, 3148-3158.

Ileana Soto (current, 2005)

Fontanesi F, Soto IC, Horn D, Barrientos A. Am J Physiol Cell Physiol. 2006 Jun 7; [Epub ahead of print] Assembly of Mitochondrial Cytochrome c Oxidase, a Complicated and Highly Regulated Cellular Process.

Satish Srinivasan, (current, 2004)

O. Y. Khan, G. Fu, A. Ismail, S. Srinivasan, X. Cao, Y. Tu, S. Lu, and Z. Nawaz. 2006. Multifunction steroid receptor coactivator, E6-associated protein, E6-AP is involved in development of the prostate gland. Mol. Endocrinol. 20, 544-559.

Krithika Subramanian, 2002

Subramanian K, Rutvisuttinunt W, Scott W, Myers RS. (Mar 15, 2003) The enzymatic basis of processivity in lambda exonuclease. Nucleic Acids Res. 31(6):1585-96

Manshu Tang, 2004

Slepak T, Tang M, Addo F, Lai K., Mol Genet Metab. 2005 Nov;86(3):360-71. Intracellular galactose-1-phosphate accumulation leads to environmental stress response in yeast model.

Gökhan Tolun, 2007

Tolun, G., Myers, R.S., A Realtime DNase Assay (ReDA) Based on PicoGreen® Fluorescence. Nucleic Acids Res. 31e111:1-6, 2003.

Feng W, Rodriguez-Menocal L, Tolun G, D'Urso G., Mol Biol Cell. 2003 Aug;14(8):3427-36. Epub 2003 May 18. Schizosacchromyces pombe Dpb2 binds to origin DNA early in S phase and is required for chromosomal DNA replication.

Ayper Tolun, 2007

Tolun, A. A., Zuo, Y., Wang, Y., Zhang, J. & Malhotra. Characterization of Oligoribonuclease active center. In preparation.

Fiedler, T. J., Nelersa, C. M., Zuo, Y., Tolun, A. A. & Malhotra, A. Structure of Oligoribonuclease is optimized for degradation of small oligonucleotides. In preparation.

Tolun A. A., Dickerson, I. M. & Malhotra, A. Overexpression and purification of human calcitonin gene-related peptide-receptor component protein in Escherichia coli. Protein Expr. Purif., 52, 167-174, 2007. (Epub: Sept 20, 2006).

Hsiao, B., Mihalak, K. B., Repicky, S. E., Everhart, D., Mederos, A. H., Malhotra, A. & Luetje, C. W. Determinants of zinc potentiation on the a4 subunit of neuronal nicotinic receptors. Molecular Pharmacology, 69, 27-36, 2006.

Zuo, Y., Wang, Y., & Malhotra, A. Crystal structure of RNase D, an exoribonuclease involved in structured RNA processing. Structure, 13, 973-984, 2005.

Helen Vincent, (current, 2002)

Vincent, H.A. and Deutscher, M.P. (2006) Substrate Recognition and Catalysis by the Exoribonuclease RNase R. J. Biol. Chem. 281 29769-29775

Fiedler, T. J., Vincent, H. A., Zuo, Y., Gavrialov, O. & Malhotra, A. Purification and crystallization of Escherichia coli oligoribonuclease. Acta Crystallographica, D, 60:736-739, 2004.

Zuo Y., Vincent, H. A., Zhang, J., Wang, Y., Deutscher, M. P. & Malhotra, A. Structural basis for processivity and single-strand specificity of RNase II. Mol. Cell, 24, 149-156, 2006.

Kemal Yariz, 2001

Ramser J, Ahearn ME, Lenski C, Yariz KO, Hellebrand H, von Rhein M, D. Clark R, Schmutzler, RK, Lichtner P, Hoffman EP, Meindl A, and Baumbach-Reardon, L. (2008). Rare Missense and Synonymous Variants in UBE1 Are Associated with X-Linked Infantile Spinal Muscular Atrophy. Amer. J. Hum Genet, 82(1):188-193.

Dressman, D., Ahearn, ME., Yariz, KO., Basterrecha H., Martinez, F., Palau, F., Barmada, MM., Clark, RD., Meindl, A, Wirth, B., Hoffman, EP., Baumbach, LL. (2007) X-linked spinal muscular atrophy (XL-SMA): clinical definition and molecular mapping. Genetics in Medicine, Jan;9(1):52-60.

Jaime Guevara-Aguirre, Arlan L Rosenbloom, Marco Guevara Aguirre, Kemal Yariz, Lisa Baumbach, Jeanette Saavedra, Jonathan Shuster. (2007). Heterozygosity for the E180 splice mutation causing growth hormone receptor deficiency (GHRD/Laron syndrome) in Ecuador is associated with reduced adult stature and no IGF-I or IGFBP3 evidence of GH insensitivity. Growth Hormone and IGF Research, March 8

Yi Zhou, 2003

Song HW, Cauffman K, Chan AP, Zhou Y, King ML, Etkin LD, Kloc M., Hermes RNA-binding protein targets RNAs-encoding proteins involved in meiotic maturation, early cleavage, and germline development. Differentiation. 2007 Jul;75(6):519-28. Epub 2007 Feb 16.

Zhou Y, Zhang J, King ML., Polarized distribution of mRNAs encoding a putative LDL receptor adaptor protein, xARH (autosomal recessive hypercholesterolemia) in Xenopus oocytes. Mech Dev. 2004 Oct;121(10):1249-58.

Zhou Y, King ML., Sending RNAs into the future: RNA localization and germ cell fate. IUBMB Life. 2004 Jan;56(1):19-27. Review.

Bruce AE, Howley C, Zhou Y, Vickers SL, Silver LM, King ML, Ho RK., The maternally expressed zebrafish T-box gene eomesodermin regulates organizer formation. Development. 2003 Nov;130(22):5503-17.

Zhou Y, Zhang J, King ML., Xenopus autosomal recessive hypercholesterolemia protein couples lipoprotein receptors with the AP-2 complex in oocytes and embryos and is required for vitellogenesis. J Biol Chem. 2003 Nov 7;278(45):44584-92. Epub 2003 Aug 27.

King ML, Zhou Y, Bubunenko M., Polarizing genetic information in the egg: RNA localization in the frog oocyte. Bioessays. 1999 Jul;21(7):546-57. Review.

Zhou Y, King ML., RNA transport to the vegetal cortex of Xenopus oocytes. Dev Biol. 1996 Oct 10;179(1):173-83.

Zhou Y, King ML., Localization of Xcat-2 RNA, a putative germ plasm component, to the mitochondrial cloud in Xenopus stage I oocytes. Development. 1996 Sep;122(9):2947-53.

Mosquera L, Forristall C, Zhou Y, King ML., A mRNA localized to the vegetal cortex of Xenopus oocytes encodes a protein with a nanos-like zinc finger domain. Development. 1993 Jan;117(1):377-86.

Yuhong Zuo, 2002

Zuo, Y., Vincent, H.A., Zhong, J., Wang, Y., Deutscher, M.P. and Malhotra, A. (2006) Structural Basis for Processivity and Single-Strand Specificity of RNase II. Mol. Cell 24, 149-156

Y. Zuo and M.P. Deutscher. 2002. “The Physiological Role of RNase T can be Explained by its Unusual Substrate Specificity”, J. Biol. Chem., 277, 29654-29661.

Y. Zuo and M.P. Deutscher. 2002. “Mechanism of Action of RNase T. I. Identification of Residues Required for Catalysis, Substrate-binding and Dimerization”, J. Biol. Chem., 277, 50155-50159.

Y. Zuo and M.P. Deutscher. 2002. “Mechanism of Action of RNase T. II. Structural and Functional Model of the Enzyme”, J. Biol. Chem., 277, 50160-50164.

Suzuki, H., Zuo, Y., Wang, J., Zhang, M. Q., Malhotra, A. & Mayeda, A. Characterization of RNase R-digested cellular RNA source that consists of lariat and circular RNAs from pre-mRNA splicing. Nucl. Acids Res., 34, e63, 2006.

Zuo, Y., Wang, Y., & Malhotra, A. Crystal structure of RNase D, an exoribonuclease involved in structured RNA processing. Structure, 13, 973-984, 2005.

Fiedler, T. J., Vincent, H. A., Zuo, Y., Gavrialov, O. & Malhotra, A. Purification and crystallization of Escherichia coli oligoribonuclease. Acta Crystallographica, D, 60:736-739, 2004.

Zuo Y., Vincent, H. A., Zhang, J., Wang, Y., Deutscher, M. P. & Malhotra, A. Structural basis for processivity and single-strand specificity of RNase II. Mol. Cell, 24, 149-156, 2006.